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Activity of a Second Trypanosoma brucei Hexokinase Is Controlled by an 18-Amino-Acid C-Terminal Tail

Trypanosoma brucei expresses two hexokinases that are 98% identical, namely, TbHK1 and TbHK2. Homozygous null TbHK2(−/−) procyclic-form parasites exhibit an increased doubling time, a change in cell morphology, and, surprisingly, a twofold increase in cellular hexokinase activity. Recombinant TbHK1...

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Detalhes bibliográficos
Main Authors: Morris, Meredith T., DeBruin, Courtney, Yang, Zhaoqing, Chambers, Jeremy W., Smith, Kerry S., Morris, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694814/
https://ncbi.nlm.nih.gov/pubmed/17028241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00146-06
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