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Shb deficient mice display an augmented T(H)2 response in peripheral CD4+ T cells

BACKGROUND: Shb, a ubiquitously expressed Src homology 2 domain-containing adaptor protein has previously been implicated in the signaling of various tyrosine kinase receptors including the TCR. Shb associates with SLP76, LAT and Vav, all important components in the signaling cascade governing T cel...

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Detalhes bibliográficos
Main Authors: Gustafsson, Karin, Calounova, Gabriela, Hjelm, Fredrik, Kriz, Vitezslav, Heyman, Birgitta, Grönvik, Kjell-Olov, Mostoslavsky, Gustavo, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024994/
https://ncbi.nlm.nih.gov/pubmed/21223549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-3
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