IgE-Mediated Enhancement of CD4(+) T Cell Responses in Mice Requires Antigen Presentation by CD11c(+) Cells and Not by B Cells

IgE antibodies, administered to mice together with their specific antigen, enhance antibody and CD4(+) T cell responses to this antigen. The effect is dependent on the low affinity receptor for IgE, CD23, and the receptor must be expressed on B cells. In vitro, IgE-antigen complexes are endocytosed...

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Main Authors: Henningsson, Frida, Ding, Zhoujie, Dahlin, Joakim S., Linkevicius, Marius, Carlsson, Fredrik, Grönvik, Kjell-Olov, Hallgren, Jenny, Heyman, Birgitta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130775/
https://ncbi.nlm.nih.gov/pubmed/21765910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021760
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