Shb deficient mice display an augmented T(H)2 response in peripheral CD4+ T cells

BACKGROUND: Shb, a ubiquitously expressed Src homology 2 domain-containing adaptor protein has previously been implicated in the signaling of various tyrosine kinase receptors including the TCR. Shb associates with SLP76, LAT and Vav, all important components in the signaling cascade governing T cel...

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Main Authors: Gustafsson, Karin, Calounova, Gabriela, Hjelm, Fredrik, Kriz, Vitezslav, Heyman, Birgitta, Grönvik, Kjell-Olov, Mostoslavsky, Gustavo, Welsh, Michael
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024994/
https://ncbi.nlm.nih.gov/pubmed/21223549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-3
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