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Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis

Aberrant regulation of T helper (Th) cell maturation is associated with a number of autoimmune conditions, including allergic disorders and rheumatoid arthritis. The Src homology domain protein B (Shb) adaptor protein was recently implicated as a regulator of Th cell differentiation. Shb is an integ...

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Detalhes bibliográficos
Main Authors: Gustafsson, Karin, Willebrand, Elsa, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137953/
https://ncbi.nlm.nih.gov/pubmed/24645804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12286
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