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Prime immunization with rotavirus VLP 2/6 followed by boosting with an adenovirus expressing VP6 induces protective immunization against rotavirus in mice

BACKGROUND: Rotavirus (RV) is the main cause of severe gastroenteritis in children. An effective vaccination regime against RV can substantially reduce morbidity and mortality. Previous studies have demonstrated the efficacy of virus-like particles formed by RV VP2 and VP6 (VLP2/6), as well as that...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhou, Hongli, Guo, Li, Wang, Min, Qu, Jianguo, Zhao, Zhendong, Wang, Jianwei, Hung, Tao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024956/
https://ncbi.nlm.nih.gov/pubmed/21205330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-3
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