Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM

Safer and more effective human rotavirus (HRV) vaccines are needed. We evaluated oral priming with attenuated WaHRV (AttHRV) followed by boosting with two intranasal (IN) doses of VP2/6 virus-like particles (2/6 VLP) with immunostimulating complexes (ISCOM) to determine if this regimen induces prote...

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Detalhes bibliográficos
Main Authors: GONZÁLEZ, A M, NGUYEN, T V, AZEVEDO, M S P, JEONG, K, AGARIB, F, IOSEF, C, CHANG, K, LOVGREN-BENGTSSON, K, MOREIN, B, SAIF, L J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808978/
https://ncbi.nlm.nih.gov/pubmed/15008967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02395.x
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