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Opioid-induced chemokine expression requires NF-κB activity: the role of PKCζ

Opioid receptor agonists induce broad immunomodulatory activity, which substantially alters host defense and the inflammatory response. Previous studies have shown that the MOR selective agonist DAMGO has the capacity to increase the expression of the proinflammatory chemokines CCL2, CCL5, and CXCL1...

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Autors principals: Happel, Christine, Kutzler, Michele, Rogers, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024904/
https://ncbi.nlm.nih.gov/pubmed/20952659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0710402
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