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The Prognostic Impact of TGF-β1, Fascin, NF-κB and PKC-ζ Expression in Soft Tissue Sarcomas

AIMS: Transforming growth factor-β (TGF-β), fascin, nuclear factor-kappa B (NF-κB) p105, protein-kinase C-zeta (PKC-ζ), partioning-defective protein-6 (Par-6), E-cadherin and vimentin are tumor promoting molecules through mechanisms involved in cell dedifferentiation. In soft tissue sarcomas, their...

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Bibliographic Details
Main Authors: Valkov, Andrej, Sorbye, Sveinung W., Kilvaer, Thomas K., Donnem, Tom, Smeland, Eivind, Bremnes, Roy M., Busund, Lill-Tove
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048407/
https://ncbi.nlm.nih.gov/pubmed/21390241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017507
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