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HoxA10 Regulates Transcription of the Gene Encoding Transforming Growth Factor β2 (TGFβ2) in Myeloid Cells
HoxA10 is a homeodomain transcription factor that is maximally expressed in myeloid progenitor cells. HoxA10 is overexpressed in a poor prognosis subset of human acute myeloid leukemia (AML) and in vivo overexpression of HoxA10 in murine bone marrow induces myeloid leukemia. HoxA10 contributes to my...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024808/ https://ncbi.nlm.nih.gov/pubmed/21087928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183251 |
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