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HoxA10 Regulates Transcription of the Gene Encoding Transforming Growth Factor β2 (TGFβ2) in Myeloid Cells

HoxA10 is a homeodomain transcription factor that is maximally expressed in myeloid progenitor cells. HoxA10 is overexpressed in a poor prognosis subset of human acute myeloid leukemia (AML) and in vivo overexpression of HoxA10 in murine bone marrow induces myeloid leukemia. HoxA10 contributes to my...

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Autori principali: Shah, Chirag A., Wang, Hao, Bei, Ling, Platanias, Leonidas C., Eklund, Elizabeth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024808/
https://ncbi.nlm.nih.gov/pubmed/21087928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183251
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