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HoxA10 Influences Protein Ubiquitination by Activating Transcription of ARIH2, the Gene Encoding Triad1

HoxA10 is a homeodomain transcription factor that is maximally expressed in myeloid progenitor cells. An increase in HoxA10 expression correlates with poor prognosis in human acute myeloid leukemia (AML). Consistent with this scenario, HoxA10 overexpression in murine bone marrow induces a myeloproli...

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Autors principals: Wang, Hao, Bei, Ling, Shah, Chirag A., Horvath, Elizabeth, Eklund, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089527/
https://ncbi.nlm.nih.gov/pubmed/21454682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213975
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