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Nf1+/− mast cells induce neurofibroma like phenotypes through secreted TGF-β signaling
Neurofibromas are common tumors found in neurofibromatosis type 1 (NF1) patients. These complex tumors are composed of Schwann cells, mast cells, fibroblasts and perineurial cells embedded in collagen that provide a lattice for tumor invasion. Genetic studies demonstrate that in neurofibromas, nulli...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024714/ https://ncbi.nlm.nih.gov/pubmed/16835260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddl165 |
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