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Nf1(−/−) Schwann Cell-Conditioned Medium Modulates Mast Cell Degranulation by c-Kit-Mediated Hyperactivation of Phosphatidylinositol 3-Kinase

Neurofibromatosis type 1 (NF1) is a common genetic disorder and is characterized by both malignant and nonmalignant neurofibromas, which are composed of Schwann cells, degranulating mast cells, fibroblasts, and extracellular matrix. We and others have previously shown that hyperactivation of the c-K...

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Detalhes bibliográficos
Main Authors: Chen, Shi, Burgin, Sarah, McDaniel, Andrew, Li, Xiaohong, Yuan, Jin, Chen, Mia, Khalaf, Waleed, Clapp, D. Wade, Yang, Feng-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993306/
https://ncbi.nlm.nih.gov/pubmed/21037083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100369
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