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Structure of the Human BK Channel Ca(2+)-Activation Apparatus at 3.0 Å Resolution
High-conductance voltage- and Ca(2+)-activated K(+) (BK) channels encode negative feedback regulation of membrane voltage and Ca(2+) signaling, playing a central role in numerous physiological processes. We determined the x-ray structure of the human BK Ca(2+) gating apparatus at a resolution of 3.0...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022345/ https://ncbi.nlm.nih.gov/pubmed/20508092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190414 |
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