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Structure of the Human BK Channel Ca(2+)-Activation Apparatus at 3.0 Å Resolution

High-conductance voltage- and Ca(2+)-activated K(+) (BK) channels encode negative feedback regulation of membrane voltage and Ca(2+) signaling, playing a central role in numerous physiological processes. We determined the x-ray structure of the human BK Ca(2+) gating apparatus at a resolution of 3.0...

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Main Authors: Yuan, Peng, Leonetti, Manuel D., Pico, Alexander R., Hsiung, Yichun, MacKinnon, Roderick
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022345/
https://ncbi.nlm.nih.gov/pubmed/20508092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190414
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