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Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation

Tumor suppression by p53 and BRCA1 involves regulation of cell cycle, apoptosis, and DNA repair and is influenced by transcriptional coactivators and post-translational modifications. Here we show that coactivator-associated arginine methyltransferase 1 (CARM1) methylates Arg 754 in the KIX region o...

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Detalhes bibliográficos
Main Authors: Lee, Young-Ho, Bedford, Mark T., Stallcup, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022263/
https://ncbi.nlm.nih.gov/pubmed/21245169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1975811
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