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Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation
Tumor suppression by p53 and BRCA1 involves regulation of cell cycle, apoptosis, and DNA repair and is influenced by transcriptional coactivators and post-translational modifications. Here we show that coactivator-associated arginine methyltransferase 1 (CARM1) methylates Arg 754 in the KIX region o...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022263/ https://ncbi.nlm.nih.gov/pubmed/21245169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1975811 |
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