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Protein methylation: a new regulator of the p53 tumor suppressor

The tumor suppressor p53 is the most frequently inactivated gene in human cancers. The p53 protein functions as a sequence-specific transcription factor to regulate key cellular processes, including cell-cycle arrest, DNA repair, apoptosis, and senescence in response to stress signals. P53 is mainta...

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Detalhes bibliográficos
Main Authors: Scoumanne, A., Chen, X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762123/
https://ncbi.nlm.nih.gov/pubmed/18581285
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