Subtilase cytotoxin, produced by Shiga-toxigenic Escherichia coli, transiently inhibits protein synthesis of Vero cells via degradation of BiP and induces cell cycle arrest at G1 by downregulation of cyclin D1

Subtilase cytotoxin (SubAB) is a AB(5) type toxin produced by Shiga-toxigenic Escherichia coli, which exhibits cytotoxicity to Vero cells. SubAB B subunit binds to toxin receptors on the cell surface, whereas the A subunit is a subtilase-like serine protease that specifically cleaves chaperone BiP/G...

Full description

Saved in:
Bibliographic Details
Main Authors: Morinaga, Naoko, Yahiro, Kinnosuke, Matsuura, Gen, Moss, Joel, Noda, Masatoshi
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021990/
https://ncbi.nlm.nih.gov/pubmed/18005237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2007.01094.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items