Fatal hemorrhage induced by subtilase cytotoxin from Shiga-toxigenic Escherichia coli

Subtilase cytotoxin (SubAB) is an AB(5) type toxin produced by a subset of Shiga-toxigenic Escherichia coli. The A subunit is a subtilase-like serine protease and cleaves an endoplasmic reticulum chaperone BiP. The B subunit binds to a receptor on the cell surface. Although SubAB is lethal for mice,...

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Hlavní autoři: Furukawa, Takeshi, Yahiro, Kinnosuke, Tsuji, Atsushi B., Terasaki, Yasuhiro, Morinaga, Naoko, Miyazaki, Masaru, Fukuda, Yuh, Saga, Tsuneo, Moss, Joel, Noda, Masatoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385872/
https://ncbi.nlm.nih.gov/pubmed/21232591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2011.01.002
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