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Fatal hemorrhage induced by subtilase cytotoxin from Shiga-toxigenic Escherichia coli
Subtilase cytotoxin (SubAB) is an AB(5) type toxin produced by a subset of Shiga-toxigenic Escherichia coli. The A subunit is a subtilase-like serine protease and cleaves an endoplasmic reticulum chaperone BiP. The B subunit binds to a receptor on the cell surface. Although SubAB is lethal for mice,...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385872/ https://ncbi.nlm.nih.gov/pubmed/21232591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2011.01.002 |
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