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New Insights into the Role of RNase L in Innate Immunity
The interferon (IFN)-inducible 2′-5′-oligoadenylate synthetase (OAS)/RNase L pathway blocks infections by some types of viruses through cleavage of viral and cellular single-stranded RNA. Viruses induce type I IFNs that initiate signaling to the OAS genes. OAS proteins are pathogen recognition recep...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc.
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021357/ https://ncbi.nlm.nih.gov/pubmed/21190483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2010.0120 |
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