Adipocyte Derived Paracrine Mediators of Mammary Ductal Morphogenesis Controlled by Retinoic Acid Receptors

We generated a transgenic (Tg)-mouse model expressing a dominant negative-(DN)-RARα, (RARαG303E) under adipocytes-specific promoter to explore the paracrine role of adipocyte retinoic acid receptors (RARs) in mammary morphogenesis. Transgenic adipocytes had reduced level of RARα, β and γ, which coin...

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Detalhes bibliográficos
Main Authors: Marzan, Christine V., Kupumbati, Tara S., Bertran, Silvina P., Samuels, TraceyAnn, Leibovitch, Boris, Lopez, Rafael Mira y, Ossowski, Liliana, Farias, Eduardo F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021183/
https://ncbi.nlm.nih.gov/pubmed/20974122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.10.018
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