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Dominant negative retinoic acid receptor initiates tumor formation in mice
BACKGROUND: Retinoic acid suppresses cell growth and promotes cell differentiation, and pharmacological retinoic acid receptor (RAR) activation is anti-tumorigenic. This begs the question of whether chronic physiological RAR activation by endogenous retinoids is likewise anti-tumorigenic. RESULTS: T...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1444935/ https://ncbi.nlm.nih.gov/pubmed/16563162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-12 |
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