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Mechanism of Inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARα agonist AM580
We hypothesized that specific activation of a single retinoic acid receptor, RARα without direct and concurrent activation of RARβ and γ, will inhibit mammary tumor oncogenesis in murine models relevant to human cancer. Fifty uniparous MMTV-neu and 50 nuliparous MMTV-wnt1 transgenic mice were treate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891995/ https://ncbi.nlm.nih.gov/pubmed/20453882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.119 |
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