Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis

INTRODUCTION: Retinoic acid signaling plays key roles in embryonic development and in maintaining the differentiated status of adult tissues. Recently, the nuclear retinoic acid receptor (RAR) isotypes α, β and γ were found to play specific functions in the expansion and differentiation of the stem...

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Hlavní autoři: Bosch, Almudena, Bertran, Silvina P, Lu, Yongke, Garcia, Avalon, Jones, Alexis M, Dawson, Marcia I, Farias, Eduardo F
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680916/
https://ncbi.nlm.nih.gov/pubmed/22920668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3247
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