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Vitamin A-dependent transcriptional activation of the nuclear factor of activated T cells c1 (NFATc1) is critical for the development and survival of B1 cells

B1 cells represent a distinct subset of B cells that produce most of the natural serum IgM and much of the gut IgA and function as an important component of early immune responses to pathogens. The development of B1 cells depends on the nuclear factor of activated T cells c1 (NFATc1), a transcriptio...

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Detalhes bibliográficos
Main Authors: Maruya, Mikako, Suzuki, Keiichiro, Fujimoto, Hanae, Miyajima, Michio, Kanagawa, Osami, Wakayama, Teruhiko, Fagarasan, Sidonia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021085/
https://ncbi.nlm.nih.gov/pubmed/21187378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014697108
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