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Vitamin A-dependent transcriptional activation of the nuclear factor of activated T cells c1 (NFATc1) is critical for the development and survival of B1 cells

B1 cells represent a distinct subset of B cells that produce most of the natural serum IgM and much of the gut IgA and function as an important component of early immune responses to pathogens. The development of B1 cells depends on the nuclear factor of activated T cells c1 (NFATc1), a transcriptio...

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Bibliografiske detaljer
Main Authors: Maruya, Mikako, Suzuki, Keiichiro, Fujimoto, Hanae, Miyajima, Michio, Kanagawa, Osami, Wakayama, Teruhiko, Fagarasan, Sidonia
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021085/
https://ncbi.nlm.nih.gov/pubmed/21187378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014697108
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