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Role for topoisomerase 1 in transcription-associated mutagenesis in yeast
High levels of transcription in Saccharomyces cerevisiae are associated with increased genetic instability, which has been linked to DNA damage. Here, we describe a pGAL-CAN1 forward mutation assay for studying transcription-associated mutagenesis (TAM) in yeast. In a wild-type background with no al...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021083/ https://ncbi.nlm.nih.gov/pubmed/21177427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012363108 |
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