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Misinsertion and bypass of thymine–thymine dimers by human DNA polymerase ι
Human DNA polymerase ι (polι) is a recently discovered enzyme that exhibits extremely low fidelity on undamaged DNA templates. Here, we show that polι is able to facilitate limited translesion replication of a thymine–thymine cyclobutane pyrimidine dimer (CPD). More importantly, however, the bypass...
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| Publicado no: | EMBO J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11013228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.19.5259 |
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