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Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
Dietary absorption is a major way for mammals to obtain cholesterol, which is mediated by Niemann-Pick C1-like 1 (NPC1L1) via vesicular endocytosis. One fundamental question in this process is how free cholesterol is efficiently taken up through the internalization of NPC1L1. Using exogenously expre...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021008/ https://ncbi.nlm.nih.gov/pubmed/21187433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014434108 |
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