Structure-Activity Relationship of Cinnamaldehyde Analogs as Inhibitors of AI-2 Based Quorum Sensing and Their Effect on Virulence of Vibrio spp

BACKGROUND: Many bacteria, including Vibrio spp., regulate virulence gene expression in a cell-density dependent way through a communication process termed quorum sensing (QS). Hence, interfering with QS could be a valuable novel antipathogenic strategy. Cinnamaldehyde has previously been shown to i...

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Detalhes bibliográficos
Main Authors: Brackman, Gilles, Celen, Shari, Hillaert, Ulrik, Van Calenbergh, Serge, Cos, Paul, Maes, Louis, Nelis, Hans J., Coenye, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020944/
https://ncbi.nlm.nih.gov/pubmed/21249192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016084
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