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Mechanisms of plasma membrane targeting of formin mDia2 through its amino terminal domains

The formin mDia2 mediates the formation of lamellipodia and filopodia during cell locomotion. The subcellular localization of activated mDia2 depends on interactions with actin filaments and the plasma membrane. We investigated the poorly understood mechanism of plasma membrane targeting of mDia2 an...

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Bibliographic Details
Main Authors: Gorelik, Roman, Yang, Changsong, Kameswaran, Vasumathi, Dominguez, Roberto, Svitkina, Tatyana
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020915/
https://ncbi.nlm.nih.gov/pubmed/21119010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-03-0256
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