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Crystal Structure of a Complex between Amino and Carboxy Terminal Fragments of mDia1: Insights into Autoinhibition of Diaphanous-Related Formins

Formin proteins direct the nucleation and assembly of linear actin filaments in a variety of cellular processes using their conserved formin homology 2 (FH2) domain. Diaphanous-related formins (DRFs) are effectors of Rho-family GTPases, and in the absence of Rho activation they are maintained in an...

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Detalles Bibliográficos
Autores principales: Nezami, Azin, Poy, Florence, Toms, Angela, Zheng, Wei, Eck, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948013/
https://ncbi.nlm.nih.gov/pubmed/20927338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012992
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