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Novel Roles of Formin mDia2 in Lamellipodia and Filopodia Formation in Motile Cells

Actin polymerization-driven protrusion of the leading edge is a key element of cell motility. The important actin nucleators formins and the Arp2/3 complex are believed to have nonoverlapping functions in inducing actin filament bundles in filopodia and dendritic networks in lamellipodia, respective...

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Bibliografiske detaljer
Main Authors: Yang, Changsong, Czech, Lubov, Gerboth, Silke, Kojima, Shin-ichiro, Scita, Giorgio, Svitkina, Tatyana
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229861/
https://ncbi.nlm.nih.gov/pubmed/18044991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050317
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