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Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality
It has been reported previously that keratin 8 (K8)-deficient mice of one strain die from a liver defect at around E12.5, while those of another strain suffer from colorectal hyperplasia. These findings have generated considerable confusion about the function of K8, K18 and K19 that are co-expressed...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302090/ https://ncbi.nlm.nih.gov/pubmed/11013209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.19.5060 |
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