Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality

It has been reported previously that keratin 8 (K8)-deficient mice of one strain die from a liver defect at around E12.5, while those of another strain suffer from colorectal hyperplasia. These findings have generated considerable confusion about the function of K8, K18 and K19 that are co-expressed...

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Vydáno v:	EMBO J
Hlavní autoři:	Hesse, Michael, Franz, Thomas, Tamai, Yoshitaka, Taketo, Makoto M., Magin, Thomas M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2000
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11013209/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.19.5060
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