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Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis
Urokinase-type plasminogen activator (uPA) is a potent catalyst of extracellular proteolysis, which also binds to a high-affinity plasma membrane receptor (uPAR). Binding of uPA may influence pericellular proteolysis and/or activate intracellular signal transduction. Transgenic mice overexpressing e...
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| Publicado no: | EMBO J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.17.4817 |
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