Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis

Urokinase-type plasminogen activator (uPA) is a potent catalyst of extracellular proteolysis, which also binds to a high-affinity plasma membrane receptor (uPAR). Binding of uPA may influence pericellular proteolysis and/or activate intracellular signal transduction. Transgenic mice overexpressing e...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Zhou, Hong-Ming, Nichols, Anthony, Meda, Paolo, Vassalli, Jean-Dominique
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2000
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.17.4817
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