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Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis

Urokinase-type plasminogen activator (uPA) is a potent catalyst of extracellular proteolysis, which also binds to a high-affinity plasma membrane receptor (uPAR). Binding of uPA may influence pericellular proteolysis and/or activate intracellular signal transduction. Transgenic mice overexpressing e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Hong-Ming, Nichols, Anthony, Meda, Paolo, Vassalli, Jean-Dominique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC302082/
https://ncbi.nlm.nih.gov/pubmed/10970872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4817
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