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Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs
Acetylation of a transcription factor has recently been shown to play a significant role in gene regulation. Here we show that GATA-3 is acetylated in T cells and that a mutation introduced into amino acids 305–307 (KRR-GATA3) creates local hypoacetylation in GATA-3. Remarkably, KRR-GATA3 possesses...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302063/ https://ncbi.nlm.nih.gov/pubmed/10970860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4676 |
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