Association of Insulin Receptor Substrate Proteins with Bcl-2 and Their Effects on Its Phosphorylation and Antiapoptotic Function

Insulin receptor substrate (IRS) proteins are docking proteins that couple growth factor receptors to various effector molecules, including phosphoinositide-3 kinase, Grb-2, Syp, and Nck. Here we show that IRS-1 associates with the loop domain of Bcl-2 and synergistically up-regulates antiapoptotic...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ueno, Hiroo, Kondo, Eisaku, Yamamoto-Honda, Ritsuko, Tobe, Kazuyuki, Nakamoto, Tetsuya, Sasaki, Ko, Mitani, Kinuko, Furusaka, Akihiro, Tanaka, Teruji, Tsujimoto, Yoshihide, Kadowaki, Takashi, Hirai, Hisamaru
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Cell Biology 2000
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC14806/
https://ncbi.nlm.nih.gov/pubmed/10679027
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια