Association of Insulin Receptor Substrate Proteins with Bcl-2 and Their Effects on Its Phosphorylation and Antiapoptotic Function

Insulin receptor substrate (IRS) proteins are docking proteins that couple growth factor receptors to various effector molecules, including phosphoinositide-3 kinase, Grb-2, Syp, and Nck. Here we show that IRS-1 associates with the loop domain of Bcl-2 and synergistically up-regulates antiapoptotic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ueno, Hiroo, Kondo, Eisaku, Yamamoto-Honda, Ritsuko, Tobe, Kazuyuki, Nakamoto, Tetsuya, Sasaki, Ko, Mitani, Kinuko, Furusaka, Akihiro, Tanaka, Teruji, Tsujimoto, Yoshihide, Kadowaki, Takashi, Hirai, Hisamaru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2000
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC14806/
https://ncbi.nlm.nih.gov/pubmed/10679027
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg