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l-Malate Production by Metabolically Engineered Escherichia coli

Escherichia coli strains (KJ060 and KJ073) that were previously developed for succinate production have now been modified for malate production. Many unexpected changes were observed during this investigation. The initial strategy of deleting fumarase isoenzymes was ineffective, and succinate contin...

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Bibliographic Details
Main Authors: Zhang, X., Wang, X., Shanmugam, K. T., Ingram, L. O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020529/
https://ncbi.nlm.nih.gov/pubmed/21097588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01971-10
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