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Reengineering Escherichia coli for Succinate Production in Mineral Salts Medium

The fermentative metabolism of glucose was redirected to succinate as the primary product without mutating any genes encoding the native mixed-acid fermentation pathway or redox reactions. Two changes in peripheral pathways were together found to increase succinate yield fivefold: (i) increased expr...

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Bibliografiska uppgifter
Huvudupphovsmän: Zhang, X., Jantama, K., Shanmugam, K. T., Ingram, L. O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794101/
https://ncbi.nlm.nih.gov/pubmed/19837840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01758-09
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