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Reengineering Escherichia coli for Succinate Production in Mineral Salts Medium

The fermentative metabolism of glucose was redirected to succinate as the primary product without mutating any genes encoding the native mixed-acid fermentation pathway or redox reactions. Two changes in peripheral pathways were together found to increase succinate yield fivefold: (i) increased expr...

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Bibliographic Details
Main Authors: Zhang, X., Jantama, K., Shanmugam, K. T., Ingram, L. O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794101/
https://ncbi.nlm.nih.gov/pubmed/19837840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01758-09
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