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Reengineering Escherichia coli for Succinate Production in Mineral Salts Medium
The fermentative metabolism of glucose was redirected to succinate as the primary product without mutating any genes encoding the native mixed-acid fermentation pathway or redox reactions. Two changes in peripheral pathways were together found to increase succinate yield fivefold: (i) increased expr...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794101/ https://ncbi.nlm.nih.gov/pubmed/19837840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01758-09 |
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