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Metabolic engineering of Escherichia coli for the production of butyric acid at high titer and productivity

BACKGROUND: Several anaerobic bacteria produce butyric acid, a commodity chemical with use in chemical, pharmaceutical, food and feed industries, using complex media with acetate as a co-product. Butyrate titer of various recombinant Escherichia coli did not exceed 10 g l(−1) in batch fermentations...

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Bibliographic Details
Published in:Biotechnol Biofuels
Main Authors: Wang, Liang, Chauliac, Diane, Moritz, Brelan E., Zhang, Guimin, Ingram, Lonnie O., Shanmugam, K. T.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429758/
https://ncbi.nlm.nih.gov/pubmed/30949238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-019-1408-9
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