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Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA

During early stages of cotranslational protein translocation across the endoplasmic reticulum (ER) membrane the ribosome is targeted to the heterotrimeric Sec61p complex, the major component of the protein-conducting channel. We demonstrate that this interaction is mediated by the 28S rRNA of the eu...

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Detalhes bibliográficos
Main Authors: Prinz, Anke, Behrens, Christina, Rapoport, Tom A., Hartmann, Enno, Kalies, Kai-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302021/
https://ncbi.nlm.nih.gov/pubmed/10775273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.8.1900
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