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The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane

Misfolded secretory proteins are transported across the endoplasmic reticulum (ER) membrane into the cytosol for degradation by proteasomes. A large fraction of proteasomes in a cell is associated with the ER membrane. We show here that binding of proteasomes to ER membranes is salt sensitive, ATP d...

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Hlavní autoři: Kalies, Kai-Uwe, Allan, Susanne, Sergeyenko, Tatiana, Kröger, Heike, Römisch, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173161/
https://ncbi.nlm.nih.gov/pubmed/15973433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600731
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