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The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane

Misfolded secretory proteins are transported across the endoplasmic reticulum (ER) membrane into the cytosol for degradation by proteasomes. A large fraction of proteasomes in a cell is associated with the ER membrane. We show here that binding of proteasomes to ER membranes is salt sensitive, ATP d...

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Bibliografske podrobnosti
Main Authors: Kalies, Kai-Uwe, Allan, Susanne, Sergeyenko, Tatiana, Kröger, Heike, Römisch, Karin
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173161/
https://ncbi.nlm.nih.gov/pubmed/15973433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600731
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