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The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane
Misfolded secretory proteins are transported across the endoplasmic reticulum (ER) membrane into the cytosol for degradation by proteasomes. A large fraction of proteasomes in a cell is associated with the ER membrane. We show here that binding of proteasomes to ER membranes is salt sensitive, ATP d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1173161/ https://ncbi.nlm.nih.gov/pubmed/15973433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600731 |
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