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Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA
During early stages of cotranslational protein translocation across the endoplasmic reticulum (ER) membrane the ribosome is targeted to the heterotrimeric Sec61p complex, the major component of the protein-conducting channel. We demonstrate that this interaction is mediated by the 28S rRNA of the eu...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302021/ https://ncbi.nlm.nih.gov/pubmed/10775273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.8.1900 |
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