A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy

Guanylyl cyclase-A (NPR-A; GC-A) is the major and possibly the only receptor for atrial natriuretic peptide (ANP) or B-type natriuretic peptide. Although mice deficient in GC-A display an elevated blood pressure, the resultant cardiac hypertrophy is much greater than in other mouse models of hyperte...

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Bibliographic Details
Main Authors: Kishimoto, Ichiro, Rossi, Kristen, Garbers, David L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC30202/
https://ncbi.nlm.nih.gov/pubmed/11226303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051625598
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