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Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart

Atrial and brain natriuretic peptides (ANP and BNP, respectively) are cardiac hormones, secretions of which are markedly upregulated during cardiac failure, making their plasma levels clinically useful diagnostic markers. ANP and BNP exert potent diuretic, natriuretic and vasorelaxant effects, which...

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Detalhes bibliográficos
Main Authors: Kishimoto, Ichiro, Tokudome, Takeshi, Horio, Takeshi, Garbers, David L, Nakao, Kazuwa, Kangawa, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803288/
https://ncbi.nlm.nih.gov/pubmed/20066148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157340309787048068
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